THE FREQUENCIES OF HAPTOGLOBIN TYPES IN FIVE POPULATIONS
نویسندگان
چکیده
منابع مشابه
The frequencies of haptoglobin types in five populations.
The first report of the existence of the plasma proteins now known as ‘ haptoglobins ’ was made by Polonovski & Jayle (1938). In subsequent studies by Jayle and his co-workers it was demonstrated that haptoglobin, which combines specifically and stoichiometrically with haemoglobin, belongs to the ct2 fraction of blood and is a glycoprotein of molecular weight approximately 155,000 (Guinand, Ton...
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The variation of the haptogIobins of human plasma was shown by Smithies (1955) and Smithies & Walker (1956, 1956) to be a Mendelian trait controlled by two alleles. These two alleles, Hpl and Hp2, co-exist generally in human populations, and their relative proportions exhibit geographic variation. Additional haptoglobin variants have been detected, but their genetic relationships to the first t...
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چکیده ندارد.
15 صفحه اولHaptoglobin phenotype frequencies in mentally retarded persons.
Haptoglobin phenotype frequencies for 887 unselected mentally retarded patients were within the range reported for normal European populations. Of these sera, 2% initially classified as anhaptoglobinemic by subjective appraisal of starch-gel electropherograms were subsequently shown to be hypohaptoglobinemic. This frequency of hypohaptoglobinemia is similar to that reported for normal populatio...
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ژورنال
عنوان ژورنال: Annals of Human Genetics
سال: 1958
ISSN: 0003-4800,1469-1809
DOI: 10.1111/j.1469-1809.1958.tb01460.x